ʻAkika Alpha-Hydroxy-Isocaproic (HICA)

ʻO HICA kekahi o nā hui bioactive he nui i loaʻa i ke kino, i ka wā e hāʻawi ʻia ai ma ke ʻano he mea hoʻopihapiha, hoʻonui nui i ka hana kanaka -- ʻo creatine kekahi laʻana.
ʻO HICA ka acronym no ka alpha-hydroxy-isocaproic acid. Ua kapa ʻia hoʻi ia he leucic acid a i ʻole DL-2-hydroxy-4-methylvaleric acid. Ke waiho ʻia ka ʻōlelo nerd, he huaʻōlelo maʻalahi loa ka hoʻomanaʻo ʻana iā HICA, a ʻo ia kekahi o nā mea nui 5 i kā mākou huahana MPO (Muscle Performance Optimizer).
I kēia manawa, me he mea lā he ʻano paʻakikī kēia akā e noho me aʻu no hoʻokahi minute. Hoʻāla ka waikawa amino leucine i ka mTOR a he mea koʻikoʻi ia no ka hoʻoulu ʻana i ka synthesis protein muscle, ʻo ia ke kī i ke kūkulu ʻana i nā ʻiʻo a i ʻole ka pale ʻana i ka haki ʻana o nā ʻiʻo. Ua lohe paha ʻoe i ka leucine ma mua no ka mea he BCAA (branched-chain amino acid) a he EAA (essential amino acid).
Hoʻopuka maoli kou kino i ka HICA i ka wā o ka metabolism o ka leucine. Hoʻohana a hoʻopili nā ʻiʻo a me nā ʻiʻo pili i ka leucine ma o kekahi o nā ala biochemical ʻelua like ʻole.
ʻO ke ala mua, ʻo ke ala KIC, lawe i ka leucine a hana iā KIC, kahi waena, kahi i hoʻololi ʻia ma hope i HICA. Lawe ke ala ʻē aʻe i ka leucine i loaʻa a hana iā HMB (β-Hydroxy β-methylbutyric acid). No laila, kapa nā kānaka ʻepekema iā HICA, a me kona hoahānau ʻike nui ʻia ʻo HMB, he mau metabolite leucine.
Manaʻo nā kānaka ʻepekema he anabolic ʻo HICA, ʻo ia hoʻi, hoʻonui ia i ka synthesis protein muscle. Hiki iā ia ke hana i kēia ma o nā ʻano like ʻole, akā hōʻike nā haʻawina he anabolic ʻo HICA no ka mea kākoʻo ia i ka hoʻāla ʻana o mTOR.
Ua lūlū ʻia hoʻi ʻo HICA no nā waiwai anti-catabolic, ʻo ia hoʻi ke kōkua nei i ka pale ʻana i ka haki ʻana o nā protein mākala i loaʻa i loko o nā ʻiʻo mākala.
I kou hoʻoikaika kino ʻana, loaʻa i kou mau ʻiʻo ka micro-trauma e hoʻopau ai i nā hunaola ʻiʻo. Manaʻo mākou a pau i nā hopena o kēia micro-trauma 24-48 mau hola ma hope o ka hoʻoikaika kino ikaika ma ke ʻano o ka ʻeha ʻiʻo lohi (DOMS). Hoʻemi nui ka HICA i kēia haki ʻana a i ʻole catabolism. ʻO ka hopena o kēia, ʻoi aku ka liʻiliʻi o ka DOMS, a ʻoi aku ka nui o nā ʻiʻo wīwī e kūkulu ai.
No laila, ma ke ʻano he mea hoʻohui, hōʻike nā haʻawina he ergogenic ka HICA. No kekahi e ʻimi nei e hoʻomaikaʻi i kā lākou hana haʻuki, pono lākou e hoʻohana i nā mea hoʻohui i hōʻoia ʻia e ka ʻepekema he ergogenic.