Alpha-Hydroxy-Isocaproic Acid (HICA)

ʻO HICA kekahi o nā mea kūlohelohe, bioactive, nā pūhui organik i loaʻa i loko o ke kino, i ka wā i hāʻawi ʻia i mea hoʻohui, hoʻomaikaʻi nui i ka hana kanaka - ʻo ka creatine kekahi laʻana.
ʻO HICA ka acronym no alpha-hydroxy-isocaproic acid. Kapa ʻia ʻo ia ka waikawa leucic a i ʻole DL-2-hydroxy-4-methylvaleric acid. Ke waiho nei i ka nerd-speak, ʻo HICA kahi huaʻōlelo maʻalahi loa e hoʻomanaʻo, a ʻo ia kekahi o nā mea nui 5 i kā mākou huahana MPO (Muscle Performance Optimizer).
I kēia manawa, ua like paha kēia me ke ʻano o ka tangent akā e pili pū me aʻu no hoʻokahi minuke. Hoʻoikaika ka amino acid leucine i ka mTOR a he mea koʻikoʻi ia no ka hoʻoulu ʻana i ka synthesis protein muscle, ʻo ia ke kī i ke kūkulu ʻana i ka ʻiʻo a i ʻole ka pale ʻana i ka haki ʻana o ka ʻiʻo. Ua lohe mua paha ʻoe i ka leucine no ka mea he BCAA (branched-chain amino acid) a me ka EAA (essential amino acid).
Hoʻopuka maoli kou kino i ka HICA i ka wā o ka metabolism o ka leucine. Hoʻohana nā ʻiʻo a me nā ʻiʻo pili i ka leucine ma o kekahi o nā ala biochemical ʻelua.
ʻO ke ala mua, ʻo ke ala KIC, lawe i ka leucine a hana i ka KIC, kahi waena, a laila hoʻololi ʻia i HICA. ʻO ke ala ʻē aʻe e lawe i ka leucine a hana i ka HMB (β-Hydroxy β-methylbutyric acid). No laila, kapa ʻia nā kānaka ʻepekema ʻo HICA, a me kāna hoahānau i ʻike ʻia ʻo HMB, nā metabolites leucine.
Manaʻo ka poʻe ʻepekema ʻo HICA he anabolic, ʻo ia ka mea e hoʻonui ai i ka synthesis protein muscle. Hiki iā ia ke hana i kēia ma o nā ʻano ʻano like ʻole, akā hōʻike nā haʻawina he anabolic ka HICA no ka mea kākoʻo ia i ka hoʻoulu ʻana o mTOR.
Ua lulu ʻia ʻo HICA no ka loaʻa ʻana o nā waiwai anti-catabolic, ʻo ia ka mea e kōkua i ka pale ʻana i ka haki ʻana o nā protein ʻiʻo i loaʻa i loko o nā ʻiʻo ʻiʻo.
I kou hoʻoikaika kino ʻana, loaʻa ka micro-trauma i kou mau ʻiʻo e wāwahi ai nā ʻiʻo. Manaʻo mākou a pau i ka hopena o kēia micro-trauma 24-48 mau hola ma hope o ka hoʻoikaika ikaika ʻana ma ke ʻano o ka hoʻopaneʻe ʻana i ka ʻeha o ka ʻiʻo (DOMS). Hoʻemi nui ʻo HICA i kēia haki a i ʻole catabolism. ʻO ka hopena o kēia mea he liʻiliʻi DOMS, a ʻoi aku ka ʻiʻo lean e kūkulu ai.
No laila, ma ke ʻano he mea hoʻohui, hōʻike nā haʻawina he ergogenic ʻo HICA. No ka mea e ʻimi nei e hoʻonui i kā lākou hana haʻuki, pono lākou e hoʻohana i nā mea hoʻohui i hōʻike ʻia e ka ʻepekema he ergogenic.