ʻO ka Astaxanthin (3,3'-dihydroxy-beta,beta-carotene-4,4'-dione) he carotenoid, i hoʻokaʻawale ʻia he lutein, i loaʻa i loko o nā ʻano microorganism like ʻole a me nā holoholona kai, a ua hoʻokaʻawale mua ʻia mai nā ʻōpae e Kuhn lāua ʻo Sorensen. He pigment momona-soluble ia e ʻike ʻia mai ka ʻalani a i ka ʻulaʻula hohonu ke kala a ʻaʻohe ona hana pro-vitamin A i loko o ke kino kanaka.
ʻO nā kumu kūlohelohe o ka astaxanthin e komo pū me ka limu, ka hū, ka iʻa sālemona, ka iʻa trout, ka krill a me ka crayfish. Loaʻa nui ka astaxanthin kalepa mai ka hū Fife, ka limu ʻulaʻula a me ka synthesis kemika. ʻO kekahi o nā kumu maikaʻi loa o ka astaxanthin kūlohelohe ʻo ia ka chlorella ʻulaʻula i hānai ʻia e ka ua, me ka nui o ka astaxanthin ma kahi o 3.8% (ma ke kaumaha maloʻo), a ʻo ka iʻa sālemona hihiu he mau kumu maikaʻi nō hoʻi o ka astaxanthin. ʻO ka hana synthetic ke kumu nui o ka astaxanthin ma muli o ke kumukūʻai kiʻekiʻe o ka mahi nui ʻana o Rhodococcus rainieri. ʻO ka hana olaola o ka astaxanthin i hana ʻia me ka synthetic he 50% wale nō o ka astaxanthin kūlohelohe.
Aia ka Astaxanthin ma ke ʻano he stereoisomers, isomers geometric, nā ʻano manuahi a me nā ʻano esterified, me nā stereoisomers (3S,3'S) a me (3R,3'R) ʻo ia ka mea nui loa ma ke ʻano. Hoʻopuka ʻo Rhodococcus rainieri i ka (3S,3'S)-isomer a ʻo Fife yeast ka mea e hana i ka (3R,3'R)-isomer.
ʻO Astaxanthin, ka wela o ka manawa
ʻO Astaxanthin ka mea hoʻohui nui i nā meaʻai hana ma Iapana. Ua ʻike ʻia nā helu helu a ka FTA ma nā hoʻolaha meaʻai hana ma Iapana i ka makahiki 2022 ua helu ʻia ka astaxanthin ma ka helu 7 ma waena o nā mea hoʻohui 10 kiʻekiʻe ma ke ʻano o ka pinepine o ka hoʻohana ʻana, a ua hoʻohana nui ʻia ma nā kahua olakino o ka mālama ʻili, ka mālama maka, ka hoʻomaha luhi, a me ka hoʻomaikaʻi ʻana i ka hana noʻonoʻo.
Ma ka Asian Nutritional Ingredients Awards 2022 a me 2023,ʻO Justgood Health Ua ʻike ʻia ka mea hoʻohui astaxanthin kūlohelohe ʻo ia ka mea hoʻohui maikaʻi loa o ka makahiki no ʻelua mau makahiki i ka lālani, ʻo ia ka mea hoʻohui maikaʻi loa ma ke ala hana noʻonoʻo i ka makahiki 2022, a ʻo ia ka mea hoʻohui maikaʻi loa ma ke ala nani waha i ka makahiki 2023. Eia kekahi, ua koho pōkole ʻia ka mea hoʻohui ma ke ala Asian Nutritional Ingredients Awards - Healthy Aging i ka makahiki 2024.
I nā makahiki i hala iho nei, ua hoʻomaka pū ka noiʻi hoʻonaʻauao e pili ana i ka astaxanthin e wela. Wahi a ka ʻikepili PubMed, i ka makahiki 1948, ua loaʻa nā haʻawina e pili ana i ka astaxanthin, akā ua haʻahaʻa ka nānā ʻana, e hoʻomaka ana i ka makahiki 2011, ua hoʻomaka ka ʻoihana kula e kālele i ka astaxanthin, me ka ʻoi aku o 100 mau puke i kēlā me kēia makahiki, a ʻoi aku ma mua o 200 i ka makahiki 2017, ʻoi aku ma mua o 300 i ka makahiki 2020, a ʻoi aku ma mua o 400 i ka makahiki 2021.
Kumu o ke kiʻi：PubMed
Ma ke ʻano o ka mākeke, e like me nā ʻike mākeke o ka wā e hiki mai ana, ua manaʻo ʻia ka nui o ka mākeke astaxanthin honua he USD 273.2 miliona i ka makahiki 2024 a ua manaʻo ʻia e hōʻea i ka USD 665.0 miliona ma ka makahiki 2034, ma kahi CAGR o 9.3% i ka wā wānana (2024-2034).
Ka mana antioxidant kiʻekiʻe loa
ʻO ke ʻano kūikawā o Astaxanthin e hāʻawi iā ia i ka mana antioxidant maikaʻi loa. Loaʻa iā Astaxanthin nā pilina pālua i hoʻohui ʻia, nā hui hydroxyl a me ketone, a he lipophilic a hydrophilic hoʻi. ʻO ka pilina pālua i hoʻohui ʻia ma ke kikowaena o ka hui e hāʻawi i nā electrons a pane me nā radical manuahi e hoʻololi iā lākou i nā huahana paʻa a hoʻopau i nā hopena kaulahao radical manuahi i nā meaola like ʻole. ʻOi aku ka maikaʻi o kāna hana olaola ma mua o nā antioxidants ʻē aʻe ma muli o kona hiki ke hoʻopili i nā membrane cell mai loko a i waho.
Kahi o ka astaxanthin a me nā antioxidants ʻē aʻe i loko o nā membrane cell
Hoʻokō ʻo Astaxanthin i ka hana antioxidant koʻikoʻi ʻaʻole wale ma o ka scavenging pololei o nā radical free, akā ma o ka hoʻoulu ʻana i ka ʻōnaehana pale antioxidant cellular ma o ka hoʻoponopono ʻana i ke ala nuclear factor erythroid 2-related factor (Nrf2). Hoʻopaʻa ʻo Astaxanthin i ka hoʻokumu ʻana o ROS a hoʻoponopono i ka hōʻike ʻana o nā enzymes oxidative stress-responsive, e like me heme oxygenase-1 (HO-1), he hōʻailona ia o ke kaumaha oxidative. Hoʻoponopono ʻia ʻo HO-1 e nā ʻano transcription factors stress-sensitive, me Nrf2, kahi e hoʻopaʻa ai i nā mea antioxidant-responsive ma ka ʻāpana promoter o nā enzymes metabolism detoxification.
ʻO ka laulā piha o nā pono a me nā noi o ka astaxanthin
1) Hoʻomaikaʻi ʻana i ka hana noʻonoʻo
Ua hōʻoia nā haʻawina he nui e hiki i ka astaxanthin ke hoʻopaneʻe a hoʻomaikaʻi paha i nā hemahema cognitive e pili ana i ka ʻelemakule maʻamau a i ʻole e hoʻēmi i ka pathophysiology o nā maʻi neurodegenerative like ʻole. Hiki i ka Astaxanthin ke hele i ka pale koko-lolo, a ua hōʻike nā haʻawina e hōʻiliʻili ka astaxanthin meaʻai i loko o ka hippocampus a me ka cerebral cortex o ka lolo ʻiole ma hope o ka lawe ʻana i hoʻokahi a hana hou ʻia, kahi e hoʻopilikia ai i ka mālama ʻana a me ka hoʻomaikaʻi ʻana i ka hana cognitive. Hoʻolaha ʻo Astaxanthin i ka hana hou ʻana o nā cell nerve a hoʻonui i ka hōʻike ʻana o ka gene o ka glial fibrillary acidic protein (GFAP), microtubule-associated protein 2 (MAP-2), brain-derived neurotrophic factor (BDNF), a me ka growth-associated protein 43 (GAP-43), nā protein i pili i ka hoʻōla ʻana o ka lolo.
ʻO nā Capsules Justgood Health Astaxanthin, me Cytisine a me Astaxanthin mai Red Algae Rainforest, e hana pū ana e hoʻomaikaʻi i ka hana cognitive o ka lolo.
2) Palekana Maka
Loaʻa i ka Astaxanthin ka hana antioxidant e hoʻopau i nā molekala radical free oxygen a hāʻawi i ka pale no nā maka. Hana like ʻo Astaxanthin me nā carotenoids ʻē aʻe e kākoʻo ana i ke olakino maka, ʻoiai ʻo lutein a me zeaxanthin. Eia kekahi, hoʻonui ka astaxanthin i ka wikiwiki o ke kahe ʻana o ke koko i ka maka, e ʻae ana i ke koko e reoxygenate i ka retina a me nā ʻiʻo maka. Ua hōʻike ʻia nā haʻawina e pale aku ka astaxanthin, me ka hui pū ʻana me nā carotenoids ʻē aʻe, i nā maka mai ka hōʻino ʻana ma waena o ka spectrum solar. Eia kekahi, kōkua ka astaxanthin i ka hōʻoluʻolu ʻole o ka maka a me ka luhi o ka ʻike.
ʻO Justgood Health Blue Light Protection Softgels, Nā mea nui: lutein, zeaxanthin, astaxanthin.
3) Mālama ʻili
ʻO ke kaumaha oxidative kahi mea nui e hoʻoulu ai i ka ʻelemakule ʻili kanaka a me ka hōʻino ʻana o ka ʻili. ʻO ke ʻano o ka ʻelemakule kūloko (chronological) a me extrinsic (light) ʻo ia ka hana ʻana o ROS, ma o ka metabolism oxidative, a ma waho ma o ka hōʻike ʻana i nā kukuna ultraviolet (UV) o ka lā. ʻO nā hanana oxidative i ka ʻelemakule ʻili e pili ana i ka hōʻino ʻana o ka DNA, nā pane mumū, ka hōʻemi ʻana o nā antioxidants, a me ka hana ʻana o nā matrix metalloproteinases (MMPs) e hoʻohaʻahaʻa i ka collagen a me ka elastin i loko o ka dermis.
Hiki i ka Astaxanthin ke kāohi pono i ka pōʻino oxidative i hoʻokumu ʻia e nā radical manuahi a me ka hoʻokomo ʻana o MMP-1 i loko o ka ʻili ma hope o ka hōʻike ʻana o UV. Ua hōʻike ʻia nā haʻawina e hiki i ka astaxanthin mai Erythrocystis rainbowensis ke hoʻonui i ka nui o ka collagen ma ke kāohi ʻana i ka hōʻike ʻana o MMP-1 a me MMP-3 i loko o nā fibroblasts dermal kanaka. Eia kekahi, ua hoʻemi ka astaxanthin i ka pōʻino DNA i hoʻokumu ʻia e ka UV a hoʻonui i ka hoʻoponopono DNA i loko o nā cell i hōʻike ʻia i ka radiation UV.
Ke hana nei ʻo Justgood Health i kekahi mau noiʻi, me nā ʻiole hulu ʻole a me nā hoʻokolohua kanaka, a ua hōʻike ʻia nā mea a pau e hōʻemi ana ka astaxanthin i ka pōʻino UV i nā papa hohonu o ka ʻili, kahi e hōʻike ai i nā hōʻailona o ka ʻelemakule ʻana o ka ʻili, e like me ka maloʻo, ka ʻili palupalu a me nā wrinkles.
4) Meaʻai haʻuki
Hiki i ka Astaxanthin ke hoʻolalelale i ka hoʻoponopono ʻana ma hope o ka hoʻoikaika kino. Ke hoʻoikaika kino a hoʻomaʻamaʻa paha ka poʻe, hana ke kino i ka nui o ROS, a inā ʻaʻole e wehe ʻia i ka manawa kūpono, hiki ke hōʻino i nā ʻiʻo a hoʻopilikia i ka hoʻōla kino ʻana, ʻoiai ʻo ka hana antioxidant ikaika o ka astaxanthin hiki ke wehe i ka ROS i ka manawa kūpono a hoʻoponopono koke i nā ʻiʻo i hōʻino ʻia.
Hoʻolauna ʻo Justgood Health i kāna Astaxanthin Complex hou, kahi hui like ʻole o ka magnesium glycerophosphate, ka huaora B6 (pyridoxine), a me ka astaxanthin e hōʻemi ana i ka ʻeha o nā ʻiʻo a me ka luhi ma hope o ka hoʻoikaika kino. Hoʻokumu ʻia ke ʻano hana a puni ka Justgood Health's Whole Algae Complex, kahi e hāʻawi ai i ka astaxanthin kūlohelohe ʻaʻole wale e pale aku i nā ʻiʻo mai ka hōʻino oxidative, akā e hoʻomaikaʻi pū i ka hana ʻana o nā ʻiʻo a hoʻomaikaʻi i ka hana haʻuki.
5) Ola Kino o ka Pūnaʻau
ʻO ke koʻikoʻi oxidative a me ka mumū ke ʻano o ka pathophysiology o ka maʻi cardiovascular atherosclerotic. Hiki i ka hana antioxidant maikaʻi loa o ka astaxanthin ke pale a hoʻomaikaʻi i ka atherosclerosis.
Kōkua ʻo Justgood Health Triple Strength Natural Astaxanthin Softgels i ka mālama ʻana i ke olakino cardiovascular ma o ka hoʻohana ʻana i ka astaxanthin kūlohelohe i loaʻa mai ka limu ʻulaʻula ānuenue, ʻo nā mea nui o ia mea e komo pū ana me ka astaxanthin, ka ʻaila niu puʻupaʻa organik a me nā tocopherols kūlohelohe.
6) Hoʻoponopono Palekana
He ʻano koʻikoʻi loa nā pūnaewele ʻōnaehana pale i ka hōʻino ʻia e nā radical manuahi. Mālama ʻo Astaxanthin i nā pale o ka ʻōnaehana pale ma ka pale ʻana i ka hōʻino ʻia e nā radical manuahi. Ua ʻike ʻia kahi noiʻi ua hana ka astaxanthin i nā immunoglobulins i loko o nā pūnaewele kanaka, a me ka hoʻohui ʻana o ka astaxanthin i loko o ke kino kanaka no 8 mau pule, ua piʻi aʻe nā pae astaxanthin i loko o ke koko, ua piʻi aʻe nā pūnaewele T a me nā pūnaewele B, ua emi ka hōʻino ʻia o ka DNA, a ua emi nui ka protein C-reactive.
Hoʻohana nā softgels Astaxanthin, ʻo ka astaxanthin maka, i ka lā kūlohelohe, ka wai i kānana ʻia e ka pele a me ka ikehu o ka lā e hana i ka astaxanthin maʻemaʻe a olakino hoʻi, hiki ke kōkua i ka hoʻoikaika ʻana i ka pale ʻana, pale i ka ʻike a me ke olakino hui.
7) Hoʻomaha i ka luhi
Ua ʻike ʻia kahi noiʻi randomized, double-blind, placebo-controlled, two-way crossover he 4 pule i hoʻolaha ai ka astaxanthin i ka hoʻōla ʻana mai ka luhi noʻonoʻo i hoʻokumu ʻia e ka visual display terminal (VDT), e hoʻēmi ana i nā pae plasma phosphatidylcholine hydroperoxide (PCOOH) kiʻekiʻe i ka wā o ka hana noʻonoʻo a me ke kino. ʻO ke kumu paha ka hana antioxidant a me ke ʻano anti-inflammatory o ka astaxanthin.
8) Ka palekana o ke akepaʻa
Loaʻa iā Astaxanthin nā hopena pale a me ka hoʻomaikaʻi ʻana i nā pilikia olakino e like me ka fibrosis ake, ka hōʻeha ischemia-reperfusion ake, a me NAFLD. Hiki iā Astaxanthin ke hoʻoponopono i nā ala hōʻailona like ʻole, e like me ka hōʻemi ʻana i ka hana JNK a me ERK-1 e hoʻomaikaʻi i ke kūʻē ʻana o ka insulin hepatic, ka pale ʻana i ka hōʻike ʻana o PPAR-γ e hōʻemi i ka synthesis momona hepatic, a me ka hoʻohaʻahaʻa ʻana i ka hōʻike ʻana o TGF-β1/Smad3 e kāohi i ka hoʻāla ʻana o HSCs a me ka fibrosis ake.
Ke kūlana o nā lula ma kēlā me kēia ʻāina
Ma Kina,ʻAstaxanthin Mai ke kumu o ke ānuenue ʻulaʻula hiki ke hoʻohana ʻia ma ke ʻano he meaʻai hou i ka meaʻai maʻamau (koe wale nō ka meaʻai pēpē), eia kekahi, ʻae pū ʻo ʻAmelika Hui Pū ʻIa, Kanada a me Iapana i ka astaxanthin e hoʻohana ʻia i ka meaʻai.
Ka manawa hoʻouna: Dec-05-2024