ʻO Astaxanthin (3,3'-dihydroxy-beta, beta-carotene-4,4'-dione) he carotenoid, i helu ʻia ma ke ʻano he lutein, loaʻa i loko o nā ʻano microorganisms a me nā holoholona moana, a ua hoʻokaʻawale ʻia mai nā ula e Kuhn a Sorensen. He puaʻa hiki ke hoʻoheheʻe ʻia i ka momona e ʻike ʻia ka ʻalani a i ka ʻulaʻula hohonu i ke kala a ʻaʻohe mea hoʻoikaika i ka huaora A i loko o ke kino kanaka.
ʻO nā kumu kūlohelohe o ka astaxanthin e pili ana i ka algae, yeast, salmon, trout, krill and crayfish. Loaʻa ka astaxanthin pāʻoihana mai ka hū Fife, ʻulaʻula algae a me ka synthesis kemika. ʻO kekahi o nā kumu maikaʻi loa o ka astaxanthin maoli ʻo ia ka chlorella ʻulaʻula i hānai ʻia, me ka maʻiʻo astaxanthin ma kahi o 3.8% (ma ke kaumaha maloʻo), a ʻo ka salmon hihiu kekahi mau kumu maikaʻi o ka astaxanthin. ʻO ka hana synthetic ke kumu nui o ka astaxanthin ma muli o ke kumukūʻai kiʻekiʻe o ka mahi nui ʻana o Rhodococcus rainieri. ʻO ka hana olaola o ka astaxanthin synthetically he 50% wale nō o ka astaxanthin maoli.
Loaʻa ka Astaxanthin ma ke ʻano he stereoisomers, geometric isomers, manuahi a me nā ʻano esterified, me nā stereoisomers (3S,3'S) a me (3R,3'R) ka mea nui loa ma ke ʻano. Hoʻopuka ʻo Rhodococcus rainieri i ka (3S,3'S) -isomer a ʻo Fife yeast e hana i ka (3R,3'R) -isomer.
Astaxanthin, ka wela o ka manawa
ʻO Astaxanthin ka hōkū i loko o nā meaʻai hana ma Iapana. Ua ʻike ʻia nā ʻikepili a ka FTA e pili ana i nā ʻōlelo hoʻolaha meaʻai ma Iapana i 2022 ua helu ʻia ʻo astaxanthin i ka helu 7 ma waena o nā mea 10 kiʻekiʻe e pili ana i ka pinepine o ka hoʻohana ʻana, a ua hoʻohana nui ʻia i nā kula olakino. mālama ʻili, mālama maka, hoʻomaha luhi, a hoʻomaikaʻi i ka hana cognitive.
Ma ka 2022 a me 2023 Asian Nutritional Ingredients Awards, ua ʻike ʻia ʻo Justgood Health's natural astaxanthin ingredient ma ke ʻano he mea maikaʻi loa o ka makahiki no ʻelua mau makahiki, ʻo ia ka mea maikaʻi loa i ka track cognitive function track i 2022, a me ka mea maikaʻi loa i ke ala nani waha ma 2023. Eia kekahi, ua hoʻopaʻa inoa ʻia ka mea hoʻohui i ka Asian Nutritional Ingredients Awards. - Ke ala ʻelemakule olakino ma 2024.
I kēia mau makahiki i hala iho nei, ua hoʻomaka ka ʻimi ʻana o ka noiʻi hoʻonaʻauao e pili ana i ka astaxanthin. Wahi a PubMedʻikepili, e like me ka 1948, aia nā haʻawina e pili ana i ka astaxanthin, akā ua haʻahaʻa ka manaʻo, e hoʻomaka ana i ka makahiki 2011, ua hoʻomaka ka academia e nānā i ka astaxanthin, me ka nui o nā puke 100 i kēlā me kēia makahiki, a ʻoi aku ma mua o 200 ma 2017, ʻoi aku. ma mua o 300 i 2020, a ʻoi aku ma mua o 400 i 2021.
Puna o ke kiʻi:PubMed
I ka ʻōlelo o ka mākeke, e like me ka ʻike mākeke Future, manaʻo ʻia ka nui o ka mākeke astaxanthin honua he $ 273.2 miliona ma 2024 a ke manaʻo ʻia nei e hōʻea i $ 665.0 miliona e 2034, ma kahi CAGR o 9.3% i ka wā wānana (2024-2034). ).
ʻOi aku ka mana antioxidant
Hāʻawi ka ʻenehana kū hoʻokahi o Astaxanthin iā ia i ka mana antioxidant maikaʻi loa. Loaʻa i ka Astaxanthin nā paʻa pālua conjugated, hydroxyl a me nā hui ketone, a he lipophilic a hydrophilic. ʻO ka paʻa pālua i hoʻohui ʻia ma ke kikowaena o ka pūhui e hāʻawi i nā electrons a pane aku me nā radical manuahi e hoʻohuli iā lākou i mau huahana paʻa a hoʻopau i nā hopena kaulahao manuahi i loko o nā mea ola like ʻole. ʻOi aku ka maikaʻi o kāna hana olaola ma mua o nā antioxidants ʻē aʻe ma muli o kona hiki ke hoʻopili i nā membrane cell mai loko i waho.
Kahi o astaxanthin a me nā antioxidants ʻē aʻe i loko o nā membrane cell
Hoʻohana ʻo Astaxanthin i ka hana antioxidant koʻikoʻi ʻaʻole wale ma o ka scavenging pololei o nā radical manuahi, akā ma o ka hoʻōla ʻana i ka ʻōnaehana pale antioxidant cellular ma o ka hoʻoponopono ʻana i ke ala nuclear factor erythroid 2-related factor (Nrf2). Hoʻopaʻa ʻo Astaxanthin i ka hoʻokumu ʻana o ROS a hoʻoponopono i ka hōʻike ʻana o nā enzymes oxidative stress-responsive, e like me heme oxygenase-1 (HO-1), kahi hōʻailona o ke koʻikoʻi oxidative. Hoʻoponopono ʻia ʻo HO-1 e nā ʻano transcription koʻikoʻi koʻikoʻi. nā kumu, me ka Nrf2, ka mea e hoʻopaʻa i nā mea antioxidant-responsive i loko o ka wahi hoʻolaha o nā enzymes metabolism detoxification.
ʻO ka piha piha o nā pono a me nā noi astaxanthin
1) Hoʻomaikaʻi i ka hana cognitive
Ua hōʻoia ka nui o nā haʻawina e hiki ke hoʻopaneʻe a hoʻomaikaʻi paha ka astaxanthin i nā hemahema cognitive e pili ana i ka ʻelemakule maʻamau a i ʻole e hōʻemi i ka pathophysiology o nā maʻi neurodegenerative. Hiki i ka Astaxanthin ke hele i ka pale koko-lolo, a ua hōʻike ʻia nā haʻawina e hōʻiliʻili ana ka astaxanthin meaʻai i ka hippocampus a me ka cerebral cortex o ka lolo ʻiole ma hope o ka hoʻohana ʻana hoʻokahi a me ka hoʻohana pinepine ʻana, hiki ke hoʻopilikia i ka mālama a me ka hoʻomaikaʻi ʻana i ka hana cognitive. Hoʻoikaika ʻo Astaxanthin i ka hoʻolaʻa hou ʻana o ke aʻalolo a hoʻonui i ka hōʻike ʻana o ka glial fibrillary acidic protein (GFAP), microtubule-associated protein 2 (MAP-2), brain-derived neurotrophic factor (BDNF), a me ka ulu-pili pūmua 43 (GAP-43), nā protein i pili i ka hoʻihoʻi ʻana o ka lolo.
ʻO Justgood Health Astaxanthin Capsules, me Cytisine a me Astaxanthin mai Red Algae Rainforest, synergize e hoʻomaikaʻi i ka hana cognitive o ka lolo.
2) Pale Maka
Loaʻa i ka Astaxanthin ka hana antioxidant e hoʻokaʻawale i nā molekala radical manuahi a hāʻawi i ka pale no nā maka. Hana like ʻo Astaxanthin me nā carotenoids ʻē aʻe e kākoʻo ana i ke olakino maka, ʻoi aku ka lutein a me ka zeaxanthin. Eia kekahi, hoʻonui ka astaxanthin i ke kahe o ke koko i ka maka, e ʻae ana i ke koko e reoxygenate i ka retina a me ka ʻiʻo o ka maka. Ua hōʻike ʻia nā haʻawina ʻo ka astaxanthin, i hui pū ʻia me nā carotenoids ʻē aʻe, pale i nā maka mai ka pōʻino ma waena o ka spectrum solar. Eia kekahi, kōkua ka astaxanthin i ka hōʻoluʻolu o ka maka a me ka luhi ʻike.
ʻO Justgood Health Blue Light Protection Softgels, nā mea nui: lutein, zeaxanthin, astaxanthin.
3) Mālama ʻili
ʻO ke koʻikoʻi oxidative kahi kumu nui o ka ʻelemakule o ke kanaka a me ka pōʻino dermal. ʻO ke ʻano o ka ʻelemakule intrinsic (chronological) a me extrinsic (light) ka hana ʻana o ROS, intrinsically ma o oxidative metabolism, a ma waho ma o ka ʻike ʻana i nā kukuna ultraviolet (UV) o ka lā. ʻO nā hanana oxidative i ka wā kahiko o ka ʻili e pili ana i ka pōʻino DNA, nā pane inflammatory, ka hōʻemi ʻana i nā antioxidants, a me ka hana ʻana o ka matrix metalloproteinases (MMPs) e hoʻohaʻahaʻa i ka collagen a me ka elastin i loko o ka dermis.
Hiki i ka Astaxanthin ke pale pono i ka poino oxidative free radical-induced a me ka hoʻokomo ʻana o MMP-1 i ka ʻili ma hope o ka hoʻolaha ʻana o UV. Ua hōʻike nā haʻawina e hiki i ka astaxanthin mai Erythrocystis rainbowensis ke hoʻonui i ka ʻike collagen ma ke kāohi ʻana i ka hōʻike o MMP-1 a me MMP-3 i nā fibroblasts dermal kanaka. Eia kekahi, ua hōʻemi ʻo astaxanthin i ka pōʻino DNA i hoʻoiho ʻia e UV a hoʻonui i ka hoʻoponopono DNA i nā cell i ʻike ʻia i ka radiation UV.
Ke alakaʻi nei ʻo Justgood Health i kekahi mau noiʻi, me nā ʻiole lauoho ʻole a me nā hoʻāʻo kanaka, ua hōʻike ʻia nā mea a pau e hōʻemi ana ka astaxanthin i ka pōʻino o UV i nā papa hohonu o ka ʻili, kahi e ʻike ʻia ai nā hōʻailona o ka ʻelemakule o ka ʻili, e like me ka maloʻo, ka ʻili a me ka ʻili. wrinkles.
4) Meaʻai haʻuki
Hiki i ka Astaxanthin ke hoʻoikaika i ka hoʻoponopono ʻana ma hope o ka hoʻomaʻamaʻa. Ke hoʻoikaika kino a hoʻomaʻamaʻa paha nā kānaka, hoʻopuka ke kino i ka nui o ka ROS, inā ʻaʻole i wehe ʻia i ka manawa, hiki ke hōʻino i nā ʻiʻo a hoʻopilikia i ka hoʻōla kino, ʻoiai hiki i ka hana antioxidant ikaika a astaxanthin ke wehe i ka ROS i ka manawa a hoʻoponopono wikiwiki i nā ʻiʻo i poino.
Hoʻolauna ʻo Justgood Health i kāna Astaxanthin Complex hou, kahi hui nui o ka magnesium glycerophosphate, ka huaʻa B6 (pyridoxine), a me ka astaxanthin e hōʻemi ana i ka ʻeha a me ka luhi ma hope o ka hoʻoikaika kino. Hoʻokumu ʻia ke kumu ma ka Justgood Health's Whole Algae Complex, nāna e hāʻawi i ka astaxanthin kūlohelohe ʻaʻole wale e pale i nā ʻiʻo mai ka pōʻino oxidative, akā hoʻomaikaʻi pū i ka hana ʻiʻo a hoʻomaikaʻi i ka hana haʻuki.
5) ʻO ke ola kino
ʻO ke kaumaha o ka oxidative a me ka mumū e hōʻike i ka pathophysiology o ka maʻi cardiovascular atherosclerotic. ʻO ka hana antioxidant maikaʻi loa o ka astaxanthin hiki ke pale a hoʻomaikaʻi i ka atherosclerosis.
ʻO Justgood Health Triple Strength Natural Astaxanthin Softgels e kōkua i ka mālama ʻana i ke olakino cardiovascular ma o ka hoʻohana ʻana i ka astaxanthin kūlohelohe i hoʻokumu ʻia mai ke anuenue ʻulaʻula algae, ʻo ia ka mea nui o ka astaxanthin, ka aila niu puʻupaʻa a me nā tocopherols maoli.
6) Hoʻoponopono i ke kino
Pilikia loa nā pūnaewele ʻōnaehana pale i ka pōʻino radical manuahi. Mālama ʻo Astaxanthin i nā pale o ka ʻōnaehana pale ma ka pale ʻana i ka pōʻino radical manuahi. A study loaʻa i ka astaxanthin i loko o kanaka keena e hana immunoglobulins, i loko o ke kino kanaka astaxanthin supplementation no 8 pule, astaxanthin pae i loko o ke koko mahuahua, T aea a me B aeaie mahuahua, DNA poino ua hoemiia, C-reactive protein nui hoemi.
ʻO Astaxanthin softgels, raw astaxanthin, hoʻohana i ka lā maoli, ka wai kānana pele a me ka ikehu o ka lā e hana ai i ka astaxanthin maʻemaʻe a olakino, hiki ke kōkua i ka hoʻonui ʻana i ka palekana, pale i ka ʻike a me ke olakino hui.
7) Hoʻopau i ka luhi
Ua ʻike ʻia kahi haʻawina crossover ʻelua mau pule he 4 mau pule, ʻelua makapō, placebo-controlled, astaxanthin i ka hoʻihoʻi ʻana mai ka pahu hōʻike hiʻohiʻona (VDT) i hoʻoulu ʻia i ka luhi noʻonoʻo, hoʻemi i ka kiʻekiʻe o ka plasma phosphatidylcholine hydroperoxide (PCOOH) kiʻekiʻe i ka wā o ka noʻonoʻo a me ke kino. hana. ʻO ke kumu paha ka hana antioxidant a me ka hana anti-inflammatory o astaxanthin.
8) Pale i ke ake
Loaʻa i ka Astaxanthin nā hopena pale a me ka hoʻomaikaʻi ʻana i nā pilikia olakino e like me ka fibrosis ate, ate ischemia-reperfusion ʻeha, a me NAFLD. Hiki i ka Astaxanthin ke hoʻoponopono i nā ala hōʻailona like ʻole, e like me ka hōʻemi ʻana i ka hana JNK a me ERK-1 e hoʻomaikaʻi ai i ka hoʻoikaika ʻana o ka insulin hepatic, kaohi ʻana i ka ʻōlelo PPAR-γ e hōʻemi i ka synthesis momona o ka hepatic, a me ka hoʻohaʻahaʻa ʻana i ka ʻōlelo TGF-β1 / Smad3 e kāohi i ka hoʻoulu ʻana o HSC a fibrosis ate.
Ke kūlana o nā hoʻoponopono i kēlā me kēia ʻāina
Ma Kina, hiki ke hoʻohana ʻia ka astaxanthin mai ke kumu o ke ānuenue ʻulaʻula liʻiliʻi ma ke ʻano he meaʻai hou i ka meaʻai maʻamau (koe ka meaʻai pēpē), ʻo ia hoʻi, ʻo ʻAmelika Hui Pū ʻIa, Kanada a me Iapana hoʻi e ʻae i ka astaxanthin e hoʻohana i ka meaʻai.
Ka manawa hoʻouna: Dec-05-2024