Hoʻololi ʻano mea | N/A |
Cas No | 71963-77-4 |
ʻO ke kimekema | C16H26O5 |
Kaumaha molekula | 298.37 |
EINECS no. | 663-549-0 |
Lae hehee | 86-88 ° C |
Lae paila | 359.79 ° C (manaʻo koʻikoʻi) |
Kahuli kiko'ī | D19.5+171°(c=2.59inCHCl3) |
ʻO ka mānoanoa | 1.0733 (manaʻo koʻikoʻi) |
Index of refraction | 1.6200(manaʻo) |
Nā kūlana mālama | lumi lumi |
Solubility | DMSO≥20mg/mL |
Ka nana aku | Pauda |
Nā huaʻōlelo like | Artemetherum/Artemtherin/Dihydroartemisininmethylether |
Solubility | Hiki i ka wai |
Māhele | ʻO ka mea kanu, mea hoʻohui, mālama ola kino |
Nā noi | Anti-malaria |
ʻO Artemether kahi lactone sesquiterpene i loaʻa i nā aʻa oArtemisia makahiki, ʻike nui ʻia he ʻawaʻawa ʻono. He lāʻau antimalarial ikaika i hoʻohana ʻia e mālama a pale i ka maʻi maʻi. ʻO Artemisinin, ka mea mua o ka artemether, i lawe mua ʻia mai ka mea kanu i ka makahiki 1970, a ua loaʻa i ka mea noiʻi Kina ʻo Tu Youyou ka makana no ka lāʻau lapaʻau ma 2015.
Ke hana nei ʻo Artemether ma ka luku ʻana i nā parasites e hoʻoulu ai i ka malaria. Hoʻokumu ʻia ka maʻi maʻi ma muli o kahi palaka protozoan i kapa ʻia ʻo Plasmodium, i lawe ʻia i ke kanaka ma o ka nahu ʻana o nā makika wahine Anopheles. I ka manawa i loko o ka hale kanaka, hoʻonui wikiwiki nā parasite i loko o ke ake a me nā keʻena koko ʻulaʻula, e hoʻoulu ai i ke kuni, ke anu, a me nā hōʻailona like ʻole o ka maʻi maʻi. Inā haʻalele ʻole ʻia, hiki i ka maʻi malaria ke make.
He ikaika loa ʻo Artemether e kūʻē i nā lāʻau kūʻē i ka lāʻau Plasmodium falciparum, ʻo ia ka mea no ka hapa nui o nā make pili i ka maʻi malaria ma ka honua holoʻokoʻa. He mea maikaʻi nō hoʻi ia e kūʻē i nā ʻano ʻano pāpaʻi Plasmodium e hoʻoulu ai i ka maʻi malaria. Hoʻohana pinepine ʻia ʻo Artemether me nā lāʻau lapaʻau ʻē aʻe, e like me ka lumefantrine, e hōʻemi i ka hopena o ka pale ʻana i ka lāʻau.
Ma waho aʻe o kona hoʻohana ʻana ma ke ʻano he lāʻau antimalarial, ua ʻike ʻia ʻo artemether i nā waiwai therapeutic ʻē aʻe. Ua hōʻike ʻia nā haʻawina he anti-inflammatory, anti-tumor, a me nā hana anti-viral. Ua hoʻohana ʻia no ka mālama ʻana i ka arthritis, lupus, a me nā maʻi autoimmune ʻē aʻe. Ua noiʻi ʻia no kona hiki ke mālama i ka COVID-19, ʻoiai ʻoi aku ka nui o ka noiʻi e hōʻoia i kona pono.
Mālama ʻia ʻo Artemether a ʻae ʻia ke hoʻohana ʻia e like me ke kuhikuhi ʻana. Eia naʻe, e like me nā lāʻau lapaʻau a pau, hiki iā ia ke hana i nā hopena ʻaoʻao. ʻO nā hopena ʻaoʻao maʻamau o ka artemether, ʻo ia ka nausea, ka luaʻi ʻana, ka noʻonoʻo, a me ke poʻo. I nā hihia koʻikoʻi, hiki iā ia ke hoʻoulu i nā hopena koʻikoʻi, e like me ka palpitations naʻau, ka hopu ʻana, a me ka pōʻino o ke ake.
I ka hopena, ʻo artemether kahi lāʻau antimalarial ikaika i hoʻololi i ka mālama ʻana a me ka pale ʻana i ka maʻi malaria. ʻO ka loaʻa ʻana ua hoʻopakele i nā ola he nui a loaʻa ka ʻike ʻia no ke kaiāulu ʻepekema. ʻO kāna mau mea therapeutic ʻē aʻe e lilo ia i moho hoʻohiki no ka mālama ʻana i nā maʻi ʻē aʻe. ʻOiai hiki iā ia ke hoʻoulu i nā hopena ʻaoʻao, ʻoi aku ka nui o kāna mau pōmaikaʻi ma mua o kona mau pilikia ke hoʻohana ʻia ma lalo o ka mālama olakino.
ʻO nā ʻano hana maʻamau i hoʻohana ʻia me nā papa, nā capsules a me nā injections. ʻO nā ʻano lāʻau lapaʻau he lāʻau antimalarial, a ʻo ka mea nui he artemether. ʻO ke kumu kumu o nā papa artemether he papa keʻokeʻo. ʻO ke ʻano o ka artemether capsule he capsule, ʻo ka pauka keʻokeʻo ka loko; ʻO ke ʻano lāʻau lapaʻau o ka artemether injection, ʻaʻole waihoʻoluʻu i ka ʻaila melemele māmā - e like me ka wai.
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